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For the L-carnitine challenge study ( n = 47), male and female homozygous APOE2-, APOE3-, and APOE4-TR mice were euthanized at 53-weeks (Supplementary Table S3)
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Cytokine Signaling Given the distinct pathways activated by ester- and ether-linked diglycerides [1], this compound serves as a precise control in experiments designed to separate the second messenger roles of diacylglycerols (from growth factors) from those of ether-linked diglycerides (from inflammatory cytokines)
In rare cases, hospitalization might be needed for proper treatment and monitoring
In pursuit of the unknown, our research group performed a variety of clinical tests on GSH level quantitation in specific brain regions (the hippocampus, frontal cortices and cingulate cortices) using non-invasive MRS techniques to evaluate GSHs role as an early diagnostic biomarker for AD
doi: 10.1016/j.mam.2008.08.006
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